The synergistic effect of NELL1 and adipose-derived stem cells on promoting bone formation in osteogenesis imperfecta treatment

Background: Osteogenesis imperfecta (OI) is a rare genetic disorder characterized by bone fragility and deformity. Mesenchymal stem cells (MSCs) infusion can improve bone performance mainly due to their differentiation into osteoblasts in OI therapy. The osteoinductive activity of NELL1 have benefit...

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Bibliographic Details
Main Authors: Yi Liu, Mingyan Ju, Zihan Wang, Jiaci Li, Chenyi Shao, Ting Fu, Yaqing Jing, Yuxia Zhao, Zhe Lv, Guang Li
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220304273