Sphingosine kinase-1 is central to androgen-regulated prostate cancer growth and survival.

Sphingosine kinase-1 is central to androgen-regulated prostate cancer growth and survival.

BACKGROUND: Sphingosine kinase-1 (SphK1) is an oncogenic lipid kinase notably involved in response to anticancer therapies in prostate cancer. Androgens regulate prostate cancer cell proliferation, and androgen deprivation therapy is the standard of care in the management of patients with advanced d...

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Bibliographic Details
Main Authors: Audrey Dayon, Leyre Brizuela, Claire Martin, Catherine Mazerolles, Nelly Pirot, Nicolas Doumerc, Leonor Nogueira, Muriel Golzio, Justin Teissié, Guy Serre, Pascal Rischmann, Bernard Malavaud, Olivier Cuvillier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2779655?pdf=render

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http://europepmc.org/articles/PMC2779655?pdf=render

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