MicroRNA-224 Promotes Pancreatic Cancer Cell Proliferation and Migration by Targeting the TXNIP-Mediated HIF1α Pathway

MicroRNA-224 Promotes Pancreatic Cancer Cell Proliferation and Migration by Targeting the TXNIP-Mediated HIF1α Pathway

Background/Aims: MicroRNAs (miRNAs) have been shown to participate in the development of pancreatic ductal adenocarcinoma (PDAC) by modulating multiple cellular processes. Increased miR-224 expression enhances proliferation and metastasis in human cancers. This study aimed to investigate the role of...

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Bibliographic Details
Main Authors: Guanghui Zhu, Lianming Zhou, Haijun Liu, Yuanzhou Shan, Xueli Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Mir-224
Pancreatic ductal adenocarcinoma
TXNIP
HIF1α
Online Access:https://www.karger.com/Article/FullText/492309

Internet

https://www.karger.com/Article/FullText/492309

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