Two-step interphase microtubule disassembly aids spindle morphogenesis

Two-step interphase microtubule disassembly aids spindle morphogenesis

Abstract Background Entry into mitosis triggers profound changes in cell shape and cytoskeletal organisation. Here, by studying microtubule remodelling in human flat mitotic cells, we identify a two-step process of interphase microtubule disassembly. Results First, a microtubule-stabilising protein,...

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Bibliographic Details
Main Authors: Nunu Mchedlishvili, Helen K. Matthews, Adam Corrigan, Buzz Baum
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Biology
Subjects:
Mitosis
Spindle assembly
Nuclear envelope breakdown
Ensconsin/MAP7
Microtubules Multipolar spindle
Online Access:http://link.springer.com/article/10.1186/s12915-017-0478-z

Internet

http://link.springer.com/article/10.1186/s12915-017-0478-z

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