Coupling between the DEAD-box RNA helicases Ded1p and eIF4A

Coupling between the DEAD-box RNA helicases Ded1p and eIF4A

Eukaryotic translation initiation involves two conserved DEAD-box RNA helicases, eIF4A and Ded1p. Here we show that S. cerevisiae eIF4A and Ded1p directly interact with each other and simultaneously with the scaffolding protein eIF4G. We delineate a comprehensive thermodynamic framework for the inte...

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Bibliographic Details
Main Authors: Zhaofeng Gao, Andrea A Putnam, Heath A Bowers, Ulf-Peter Guenther, Xuan Ye, Audrey Kindsfather, Angela K Hilliker, Eckhard Jankowsky
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-08-01
Series:eLife
Subjects:
helicase
RNA
translation
Online Access:https://elifesciences.org/articles/16408

Internet

https://elifesciences.org/articles/16408

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