Precision-engineered Peptide and Protein Analogs: Establishing a New Discovery Platform for Potent GPCR Modulators

Numerous members of the human G protein-coupled receptor (GPCR) superfamily are receptors of therapeutic interest. GPCRs are considered to be highly tractable for drug discovery, representing the targets of approximately one-third of currently licensed drugs. These successful drug discovery outcomes...

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Bibliographic Details
Main Authors: Kalyan Bharati Akondi, Marianne Paolini-Bertrand, Oliver Hartley
Format: Article
Language:deu
Published: Swiss Chemical Society 2021-06-01
Series:CHIMIA
Subjects:
Online Access:https://www.ingentaconnect.com/contentone/scs/chimia/2021/00000075/00000006/art00005