Genetic Association Between Alzheimer’s Disease Risk Variant of the PICALM Gene and EEG Functional Connectivity in Non-demented Adults

Genetic Association Between Alzheimer’s Disease Risk Variant of the PICALM Gene and EEG Functional Connectivity in Non-demented Adults

Genome wide association studies (GWAS) have identified and validated the association of the PICALM genotype with Alzheimer’s disease (AD). The PICALM rs3851179 A allele is thought to have a protective effect, whereas the G allele appears to confer risk for AD. The influence of the PICALM genotype on...

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Bibliographic Details
Main Authors: Natalya Ponomareva, Tatiana Andreeva, Maria Protasova, Rodion Konovalov, Marina Krotenkova, Daria Malina, Andrey Mitrofanov, Vitaly Fokin, Sergey Illarioshkin, Evgeny Rogaev
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Neuroscience
Subjects:
PICALM genotype
EEG connectivity
alpha rhythm
Alzheimer’s disease
genetic predisposition
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00324/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2020.00324/full

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