Chronic Hypoxia Enhances Expression and Activity of Mitochondrial Creatine Kinase and Hexokinase in the Rat Ventricular Myocardium

Chronic Hypoxia Enhances Expression and Activity of Mitochondrial Creatine Kinase and Hexokinase in the Rat Ventricular Myocardium

Background: Creatine kinase (CK) and hexokinase (HK) play a key role in myocardial energy homeostasis. We aimed to determine CK and HK expression and enzyme activity in the left (LV) and right (RV) ventricles of rats adapted for 3 weeks to normobaric hypoxia (10 % O2) either continuously (CNH) or in...

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Bibliographic Details
Main Authors: Petra Waskova-Arnostova, Dita Kasparova, Barbara Elsnicova, Jiri Novotny, Jan Neckar, Frantisek Kolar, Jitka Zurmanova
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Right ventricle
Left ventricle
Creatine kinase
Mitochondria co-localization
Normobaric hypoxia
Hexokinase
Online Access:http://www.karger.com/Article/FullText/356671

Internet

http://www.karger.com/Article/FullText/356671

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