Placental Epigenome-Wide Association Study Identified Loci Associated with Childhood Adiposity at 3 Years of Age

Placental Epigenome-Wide Association Study Identified Loci Associated with Childhood Adiposity at 3 Years of Age

The aim of this study was to identify placental DNA methylation (DNAm) variations associated with adiposity at 3 years of age. We quantified placental DNAm using the Infinium MethylationEPIC BeadChips. We assessed associations between DNAm at single-CpGs and skinfold thickness using robust linear re...

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Bibliographic Details
Main Authors: Valérie Gagné-Ouellet, Edith Breton, Kathrine Thibeault, Carol-Ann Fortin, Véronique Desgagné, Élise Girard Tremblay, Andres Cardenas, Renée Guérin, Patrice Perron, Marie-France Hivert, Luigi Bouchard
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
skinfolds thickness
epigenetics
fetal programming
DNA methylation
transcriptomics
EPIC array
Online Access:https://www.mdpi.com/1422-0067/21/19/7201

Internet

https://www.mdpi.com/1422-0067/21/19/7201

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