EAF2 and p53 Co-Regulate STAT3 Activation in Prostate Cancer

EAF2 and p53 Co-Regulate STAT3 Activation in Prostate Cancer

The tumor suppressor genes EAF2 and p53 are frequently dysregulated in prostate cancers. Recently, we reported that concurrent p53 nuclear staining and EAF2 downregulation were associated with high Gleason score. Combined loss of EAF2 and p53 in a murine model induced prostate tumors, and concurrent...

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Bibliographic Details
Main Authors: Laura E. Pascal, Yao Wang, Mingming Zhong, Dan Wang, Anish Bhaswanth Chakka, Zhenyu Yang, Feng Li, Qiong Song, Lora H. Rigatti, Srilakshmi Chaparala, Uma Chandran, Anil V. Parwani, Zhou Wang
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558617305584

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http://www.sciencedirect.com/science/article/pii/S1476558617305584

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