Influence of different chromosomal abnormalities in Ph-positive bone marrow cells on the chronic myeloid leukemia course during tyrosine kinase inhibitors therapy

<p>The additional molecular and chromosomal abnormalities (ACA) in Phositive cells usually considered as a genetic marker of chronic myeloid leukemia (CML) progression. 457 patients in different CML phases received tyrosine kinase inhibitors (1st and 2nd generation) were studied. During therap...

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Main Authors: O. Yu. Vinogradova, E. A. Aseeva, A. V. Vorontsova, A. G. Turkina, A. L. Neverova, O. V. Lazareva, E. Yu. Chelysheva, G. A. Gusarova, T. I. Kolosheinova, L. Yu. Kolosova, S. R. Goryacheva, M. V. Vakhrusheva, S. M. Kulikov, I. A. Tishchenko, L. V. Dyachenko, A. I. Udovichenko, G. A. Alimova, E. V. Kleina, L. A. Grebenyuk, M. L. Konnova, S. Yu. Smirnova, N. D. Khoroshko, E. V. Domracheva
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Onkogematologiâ
Subjects:
Online Access:http://oncohematology.abvpress.ru/index.php/ongm/article/view/73