Ion Mobility Coupled to a Time-of-Flight Mass Analyzer Combined With Fragment Intensity Predictions Improves Identification of Classical Bioactive Peptides and Small Open Reading Frame-Encoded Peptides

Ion Mobility Coupled to a Time-of-Flight Mass Analyzer Combined With Fragment Intensity Predictions Improves Identification of Classical Bioactive Peptides and Small Open Reading Frame-Encoded Peptides

Bioactive peptides exhibit key roles in a wide variety of complex processes, such as regulation of body weight, learning, aging, and innate immune response. Next to the classical bioactive peptides, emerging from larger precursor proteins by specific proteolytic processing, a new class of peptides o...

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Bibliographic Details
Main Authors: Marlies K. R. Peeters, Geert Baggerman, Ralf Gabriels, Elise Pepermans, Gerben Menschaert, Kurt Boonen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
peptidomics
proteogenomics analysis
neuropeptide
sORF-encoded polypeptide (SEP)
micropeptide
spectral intensity prediction
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.720570/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.720570/full

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