TUSC5 regulates insulin-mediated adipose tissue glucose uptake by modulation of GLUT4 recycling

TUSC5 regulates insulin-mediated adipose tissue glucose uptake by modulation of GLUT4 recycling

Objective: Failure to properly dispose of glucose in response to insulin is a serious health problem, occurring during obesity and is associated with type 2 diabetes development. Insulin-stimulated glucose uptake is facilitated by the translocation and plasma membrane fusion of vesicles containing g...

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Bibliographic Details
Main Authors: Nigel Beaton, Carla Rudigier, Hansjörg Moest, Sebastian Müller, Nadja Mrosek, Eva Röder, Gottfried Rudofsky, Thomas Rülicke, Jozef Ukropec, Barbara Ukropcova, Robert Augustin, Heike Neubauer, Christian Wolfrum
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Molecular Metabolism
Subjects:
Obesity
Glucose uptake
Type 2 diabetes
Insulin resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S221287781500157X

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http://www.sciencedirect.com/science/article/pii/S221287781500157X

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