Sleep disturbances in highly stress reactive mice: Modeling endophenotypes of major depression

<p>Abstract</p> <p>Background</p> <p>Neuronal mechanisms underlying affective disorders such as major depression (MD) are still poorly understood. By selectively breeding mice for high (HR), intermediate (IR), or low (LR) reactivity of the hypothalamic-pituitary-adrenoc...

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Bibliographic Details
Main Authors: Landgraf Rainer, Holsboer Florian, Ruschel Jörg, Romanowski Christoph PN, Touma Chadi, Fenzl Thomas, Kimura Mayumi, Yassouridis Alexander
Format: Article
Language:English
Published: BMC 2011-03-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/12/29