Genetic Predisposition to Sporadic Cancer: How to Handle Major Effects of Minor Genes?
Predisposition to non-familial, sporadic cancer is strongly influenced by multiple tumor susceptibility genes (TSGs), each with apparently minor effects on the cancer phenotype. Sequence analysis of the human genome has yielded numerous single nucleotide polymorphisms (SNPs), raising the expectation...
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2005-01-01
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| Series: | Cellular Oncology |
| Online Access: | http://dx.doi.org/10.1155/2005/737191 |