Osteopontin plays a pivotal role in increasing severity of respiratory syncytial virus infection.

The molecular mechanisms underlying susceptibility to severe respiratory syncytial virus (RSV) infection remain poorly understood. Herein, we report on the role of osteopontin (OPN) in regulation of RSV infection in human epithelial cells and how interleukin-1 beta (IL-1β), a cytokine secreted soon...

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Bibliographic Details
Main Authors: Viviana Sampayo-Escobar, Ryan Green, Michael B Cheung, Raminder Bedi, Subhra Mohapatra, Shyam S Mohapatra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5909912?pdf=render