Lysophosphatidic Acid Accelerates Bovine In Vitro-Produced Blastocyst Formation through the Hippo/YAP Pathway

Lysophosphatidic Acid Accelerates Bovine In Vitro-Produced Blastocyst Formation through the Hippo/YAP Pathway

The segregation of trophectoderm (TE) and inner cell mass in early embryos is driven primarily by the transcription factor CDX2. The signals that trigger CDX2 activation are, however, less clear. In mouse embryos, the Hippo-YAP signaling pathway is important for the activation of CDX2 expression; it...

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Bibliographic Details
Main Authors: Bo Yu, Helena T. A. van Tol, Christine H. Y. Oei, Tom A. E. Stout, Bernard A. J. Roelen
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
bovine
lineage segregation
LPA
YAP
CDX2
trophectoderm
Online Access:https://www.mdpi.com/1422-0067/22/11/5915

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https://www.mdpi.com/1422-0067/22/11/5915

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