Establishment of a novel gene panel as a biomarker of immune checkpoint inhibitor response

Establishment of a novel gene panel as a biomarker of immune checkpoint inhibitor response

Abstract Objective Immune checkpoint inhibitors (ICIs) have become the standard of care in various cancers, although the predictive tool is still unknown. Methods This study aimed to develop a novel gene panel by selecting DNA damage response (DDR) genes from the Catalogue of Somatic Mutations in Ca...

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Bibliographic Details
Main Authors: Yi‐Ru Pan, Chiao‐En Wu, Yu‐Chao Wang, Yi‐Chen Yeh, Meng‐Lun Lu, Yi‐Ping Hung, Yee Chao, Da‐Wei Yeh, Chien‐Hsing Lin, Jason Chia‐Hsun Hsieh, Ming‐Huang Chen, Chun‐Nan Yeh
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Clinical & Translational Immunology
Subjects:
cell‐free DNA
DNA repair gene
gene panel
immune checkpoint inhibitor
tumor mutational burden
Online Access:https://doi.org/10.1002/cti2.1145

Internet

https://doi.org/10.1002/cti2.1145

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