Comparative Analysis of the Cytotoxic Effects of Okadaic Acid-Group Toxins on Human Intestinal Cell Lines

The phycotoxin, okadaic acid (OA) and dinophysistoxin 1 and 2 (DTX-1 and -2) are protein phosphatase PP2A and PP1 inhibitors involved in diarrhetic shellfish poisoning (DSP). Data on the toxicity of the OA-group toxins show some differences with respect to the in vivo acute toxicity between the toxi...

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Bibliographic Details
Main Authors: Pierre-Jean Ferron, Kevin Hogeveen, Valérie Fessard, Ludovic Le Hégarat
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/12/8/4616