Functional analysis of sepiapterin reductase in Drosophila melanogaster

Sepiapterin reductase (SR) is a key enzyme involved in the biosynthesis of tetrahydrobiopterin (BH4), an essential cofactor for the synthesis of important biogenic amines, including catecholamines and serotonin. BH4 deficiencies have been implicated in several neurological disorders. Here, we charac...

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Bibliographic Details
Main Authors: Kim Kiyoung, Kim Heuijong, Yim Jeongbin
Format: Article
Language:English
Published: De Gruyter 2015-06-01
Series:Pteridines
Subjects:
akt
bh4
Online Access:https://doi.org/10.1515/pterid-2014-0018