Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1

Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1

Brief periods of sleep loss have long-lasting consequences such as impaired memory consolidation. Structural changes in synaptic connectivity have been proposed as a substrate of memory storage. Here, we examine the impact of brief periods of sleep deprivation on dendritic structure. In mice, we fin...

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Bibliographic Details
Main Authors: Robbert Havekes, Alan J Park, Jennifer C Tudor, Vincent G Luczak, Rolf T Hansen, Sarah L Ferri, Vibeke M Bruinenberg, Shane G Poplawski, Jonathan P Day, Sara J Aton, Kasia Radwańska, Peter Meerlo, Miles D Houslay, George S Baillie, Ted Abel
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-08-01
Series:eLife
Subjects:
Sleep loss
synaptic plasticity
hippocampus
Online Access:https://elifesciences.org/articles/13424

Internet

https://elifesciences.org/articles/13424

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