Complement Component C3 Participates in Early Stages of Niemann–Pick C Mouse Liver Damage
Niemann−Pick type C (NPC), a lysosomal storage disorder, is mainly caused by mutations in the <i>NPC1</i> gene. Niemann−Pick type C patients and mice show intracellular cholesterol accumulation leading to hepatic failure with increased inflammatory response. The compl...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-03-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/21/6/2127 |