Nuclear isoform of FGF13 regulates post-natal neurogenesis in the hippocampus through an epigenomic mechanism

Nuclear isoform of FGF13 regulates post-natal neurogenesis in the hippocampus through an epigenomic mechanism

Summary: The hippocampus is one of two niches in the mammalian brain with persistent neurogenesis into adulthood. The neurogenic capacity of hippocampal neural stem cells (NSCs) declines with age, but the molecular mechanisms of this process remain unknown. In this study, we find that fibroblast gro...

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Bibliographic Details
Main Authors: Qiao-qiao Yang, Ying-qi Zhai, Hai-fang Wang, Yu-chen Cai, Xin-yue Ma, Yan-qing Yin, Yan-dong Li, Guo-min Zhou, Xu Zhang, Gang Hu, Jia-wei Zhou
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Cell Reports
Subjects:
FGF13
dentate gyrus
neurogenesis
neural stem cells
ARID1B
chromatin modification
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721004666

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http://www.sciencedirect.com/science/article/pii/S2211124721004666

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