Cajaninstilbene Acid Ameliorates Cognitive Impairment Induced by Intrahippocampal Injection of Amyloid-β1–42 Oligomers

Cajaninstilbene Acid Ameliorates Cognitive Impairment Induced by Intrahippocampal Injection of Amyloid-β1–42 Oligomers

Amyloid-β1–42 (Aβ1–42) oligomers play an important role at the early stage of Alzheimer’s disease (AD) and have been a vital target in the development of therapeutic drugs for AD. Cajaninstilbene acid (CSA), a major bioactive stilbene isolated from pigeon pea (Cajanus cajan) leaves, exerted the neur...

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Bibliographic Details
Main Authors: Li-Sha Wang, Xue Tao, Xin-Min Liu, Yun-Feng Zhou, Meng-Di Zhang, Yong-Hong Liao, Rui-Le Pan, Qi Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Pharmacology
Subjects:
Alzheimer’s disease
amyloid-β oligomer
cajaninstilbene acid
cognition
microglia
astrocyte
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01084/full

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https://www.frontiersin.org/article/10.3389/fphar.2019.01084/full

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