Genomic and non-genomic pathways are both crucial for peak induction of neurite outgrowth by retinoids

Genomic and non-genomic pathways are both crucial for peak induction of neurite outgrowth by retinoids

Abstract Retinoic acid (RA) is the active metabolite of vitamin A and essential for many physiological processes, particularly the induction of cell differentiation. In addition to regulating genomic transcriptional activity via RA receptors (RARs) and retinoid X receptors (RXRs), non-genomic mechan...

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Bibliographic Details
Main Authors: Thabat Khatib, Pietro Marini, Sudheer Nunna, David R. Chisholm, Andrew Whiting, Christopher Redfern, Iain R. Greig, Peter McCaffery
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Cell Communication and Signaling
Subjects:
Retinoic acid
Vitamin a
Erk1/2
Neurite outgrowth
RAR
Transcription
Online Access:http://link.springer.com/article/10.1186/s12964-019-0352-4

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http://link.springer.com/article/10.1186/s12964-019-0352-4

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