MicroRNA-106a-5p Inhibited C2C12 Myogenesis via Targeting PIK3R1 and Modulating the PI3K/AKT Signaling

MicroRNA-106a-5p Inhibited C2C12 Myogenesis via Targeting PIK3R1 and Modulating the PI3K/AKT Signaling

The microRNA (miR)-17 family is widely expressed in mammalian tissues and play important roles in various physiological and pathological processes. Here, the functions of miR-106a-5p, a member of miR-17 family, were explored during myogenic differentiation in C2C12 cell line. First, miR-106a-5p was...

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Bibliographic Details
Main Authors: Xiao Li, Youbo Zhu, Huifang Zhang, Guangjun Ma, Guofang Wu, Aoqi Xiang, Xin’E. Shi, Gong She Yang, Shiduo Sun
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Genes
Subjects:
miR-106a-5p
myogenic differentiation
muscle atrophy
PIK3R1
C2C12 cell line
Online Access:http://www.mdpi.com/2073-4425/9/7/333

Internet

http://www.mdpi.com/2073-4425/9/7/333

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