The PTEN phosphatase controls intestinal epithelial cell polarity and barrier function: role in colorectal cancer progression.

The PTEN phosphatase controls intestinal epithelial cell polarity and barrier function: role in colorectal cancer progression.

The PTEN phosphatase acts on phosphatidylinositol 3,4,5-triphosphates resulting from phosphatidylinositol 3-kinase (PI3K) activation. PTEN expression has been shown to be decreased in colorectal cancer. Little is known however as to the specific cellular role of PTEN in human intestinal epithelial c...

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Bibliographic Details
Main Authors: Marie-Josée Langlois, Sébastien Bergeron, Gérald Bernatchez, François Boudreau, Caroline Saucier, Nathalie Perreault, Julie C Carrier, Nathalie Rivard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3009737?pdf=render

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http://europepmc.org/articles/PMC3009737?pdf=render

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