PMA Induces Vaccine Adjuvant Activity by the Modulation of TLR Signaling Pathway

Toll-like receptor (TLR) ligands are being developed for use as vaccine adjuvants and as immunomodulators because of their ability to stimulate innate and adaptive immune responses. Flagellin, a TLR5 ligand, was reported to show potent mucosal vaccine adjuvant activity. To identify ligands that pote...

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Bibliographic Details
Main Authors: Dool-Ri Oh, Hu Won Kang, Jong-Ro Kim, Sunoh Kim, In-Kyu Park, Joon Haeng Rhee, Won Keun Oh, Young Ran Kim
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2014/406514