Modulation of proinflammatory activity by the engineered cationic antimicrobial peptide WLBU-2 [v1; ref status: indexed, http://f1000r.es/xq]

Modulation of proinflammatory activity by the engineered cationic antimicrobial peptide WLBU-2 [v1; ref status: indexed, http://f1000r.es/xq]

Background: Host-derived (LL-37) and synthetic (WLBU-2) cationic antimicrobial peptides (CAPs) are known for their membrane-active bactericidal properties. LL-37 is an important mediator for immunomodulation, while the mechanism of action of WLBU-2 remains unclear. Objective: To determine if WLBU-2...

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Bibliographic Details
Main Authors: Shruti M Paranjape, Thomas W Lauer, Ronald C Montelaro, Timothy A Mietzner, Neeraj Vij
Format: Article
Language:English
Published: F1000 Research Ltd 2013-02-01
Series:F1000Research
Subjects:
Antimicrobials & Drug Resistance
Immunity to Infections
Immunomodulation
Medical Microbiology
Online Access:http://f1000research.com/articles/2-36/v1

Internet

http://f1000research.com/articles/2-36/v1

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