Phenotypic and Functional Characterization of Müller Glia Isolated from Induced Pluripotent Stem Cell‐Derived Retinal Organoids: Improvement of Retinal Ganglion Cell Function upon Transplantation

Phenotypic and Functional Characterization of Müller Glia Isolated from Induced Pluripotent Stem Cell‐Derived Retinal Organoids: Improvement of Retinal Ganglion Cell Function upon Transplantation

Abstract Glaucoma is one of the leading causes of blindness, and there is an ongoing need for new therapies. Recent studies indicate that cell transplantation using Müller glia may be beneficial, but there is a need for novel sources of cells to provide therapeutic benefit. In this study, we have is...

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Bibliographic Details
Main Authors: Karen Eastlake, Weixin Wang, Hari Jayaram, Celia Murray‐Dunning, Amanda J. F. Carr, Conor M. Ramsden, Anthony Vugler, Katrina Gore, Nadine Clemo, Mark Stewart, Pete Coffey, Peng T. Khaw, G. Astrid Limb
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Stem Cells Translational Medicine
Subjects:
Stem cells
Induced pluripotent stem cell
Müller glia
Glaucoma
Regeneration
Online Access:https://doi.org/10.1002/sctm.18-0263

Internet

https://doi.org/10.1002/sctm.18-0263

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