Shape-induced terminal differentiation of human epidermal stem cells requires p38 and is regulated by histone acetylation.

Shape-induced terminal differentiation of human epidermal stem cells requires p38 and is regulated by histone acetylation.

Engineered model substrates are powerful tools for examining interactions between stem cells and their microenvironment. Using this approach, we have previously shown that restricted cell adhesion promotes terminal differentiation of human epidermal stem cells via activation of serum response factor...

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Bibliographic Details
Main Authors: John T Connelly, Ajay Mishra, Julien E Gautrot, Fiona M Watt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3206954?pdf=render

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http://europepmc.org/articles/PMC3206954?pdf=render

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