Retrograde Transgene Expression via Neuron-Specific Lentiviral Vector Depends on Both Species and Input Projections

Retrograde Transgene Expression via Neuron-Specific Lentiviral Vector Depends on Both Species and Input Projections

For achieving retrograde gene transfer, we have so far developed two types of lentiviral vectors pseudotyped with fusion envelope glycoprotein, termed HiRet vector and NeuRet vector, consisting of distinct combinations of rabies virus and vesicular stomatitis virus glycoproteins. In the present stud...

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Bibliographic Details
Main Authors: Yukiko Otsuka, Hitomi Tsuge, Shiori Uezono, Soshi Tanabe, Maki Fujiwara, Miki Miwa, Shigeki Kato, Katsuki Nakamura, Kazuto Kobayashi, Ken-ichi Inoue, Masahiko Takada
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Viruses
Subjects:
lentiviral vector
pseudotyping
retrograde gene transfer
cerebral cortex
thalamus
neuron specificity
Online Access:https://www.mdpi.com/1999-4915/13/7/1387

Internet

https://www.mdpi.com/1999-4915/13/7/1387

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