Transcription Factor Homeobox D9 Drives the Malignant Phenotype of HPV18-Positive Cervical Cancer Cells via Binding to the Viral Early Promoter

Persistent infections with two types of human papillomaviruses (HPV), HPV16 and HPV18, are the most common cause of cervical cancer (CC). Two viral early genes, <i>E6</i> and <i>E7</i>, are associated with tumor development, and expressions of <i>E6</i> and <i&...

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Main Authors: Shigenori Hayashi, Takashi Iwata, Ryotaro Imagawa, Masaki Sugawara, Guanliang Chen, Satoko Tanimoto, Yo Sugawara, Ikumo Tanaka, Tomoya Matsui, Hiroshi Nishio, Masaru Nakamura, Yuki Katoh, Seiichiro Mori, Iwao Kukimoto, Daisuke Aoki
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
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Online Access:https://www.mdpi.com/2072-6694/13/18/4613