Evaluating the probability of CRISPR‐based gene drive contaminating another species

Abstract The probability D that a given clustered regularly interspaced short palindromic repeats (CRISPR)‐based gene drive element contaminates another, nontarget species can be estimated by the following Drive Risk Assessment Quantitative Estimate (DRAQUE) Equation: D=hyb+transf×express×cut×flank×...

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Bibliographic Details
Main Authors: Virginie Courtier‐Orgogozo, Antoine Danchin, Pierre‐Henri Gouyon, Christophe Boëte
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Evolutionary Applications
Subjects:
Online Access:https://doi.org/10.1111/eva.12939