Practical Calling Approach for Exome Array-Based Genome-Wide Association Studies in Korean Population

Exome-based genotyping arrays are cost-effective and have recently been used as alternative platforms to whole-exome sequencing. However, the automated clustering algorithm in an exome array has a genotype calling problem in accuracy for identifying rare and low-frequency variants. To address these...

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Bibliographic Details
Main Authors: Tae-Joon Park, Lyong Heo, Sanghoon Moon, Young Jin Kim, Ji Hee Oh, Sohee Han, Bong-Jo Kim
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:International Journal of Genomics
Online Access:http://dx.doi.org/10.1155/2015/421715