Shear-induced damped oscillations in an epithelium depend on actomyosin contraction and E-cadherin cell adhesion

Shear forces between cells occur during global changes in multicellular organization during morphogenesis and tissue growth, yet how cells sense shear forces and propagate a response across a tissue is unknown. We found that applying exogenous shear at the midline of an epithelium induced a local, s...

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Bibliographic Details
Main Authors: Ehsan Sadeghipour, Miguel A Garcia, William James Nelson, Beth L Pruitt
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/39640