Missense Mutations in Cancer Predisposing Genes: Can We Make Sense of Them?

<p>Abstract</p> <p>In the analysis of genes associated with predispositions to malignancy the causative status of mutations can be made relatively easily where it is obvious that there is a clear disruption in the coding sequence of the gene. Difficulties arise, however, if missens...

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Bibliographic Details
Main Authors: Scott Rodney J, Meldrum Cliff J
Format: Article
Language:English
Published: BMC 2005-08-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Online Access:http://www.hccpjournal.com/content/3/3/123