Effect of Age on Blood Rheology in Sickle Cell Anaemia and Sickle Cell Haemoglobin C Disease: A Cross-Sectional Study.

Effect of Age on Blood Rheology in Sickle Cell Anaemia and Sickle Cell Haemoglobin C Disease: A Cross-Sectional Study.

OBJECTIVES:Blood rheology plays a key role in the pathophysiology of sickle cell anaemia (SS) and sickle cell haemoglobin C disease (SC), but its evolution over the lifespan is unknown. MATERIALS AND METHODS:Blood viscosity, red blood cell (RBC) deformability and aggregation, foetal haemoglobin (HbF...

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Main Authors: Céline Renoux, Marc Romana, Philippe Joly, Séverine Ferdinand, Camille Faes, Nathalie Lemonne, Sarah Skinner, Nathalie Garnier, Maryse Etienne-Julan, Yves Bertrand, Marie Petras, Giovanna Cannas, Lydia Divialle-Doumdo, Elie Nader, Daniela Cuzzubbo, Yann Lamarre, Alexandra Gauthier, Xavier Waltz, Kamila Kebaili, Cyril Martin, Arnaud Hot, Marie-Dominique Hardy-Dessources, Vincent Pialoux, Philippe Connes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4927160?pdf=render

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http://europepmc.org/articles/PMC4927160?pdf=render

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