Accumulation of Amyloid-Like Aβ in AEL (Autophagy–Endosomal–Lysosomal) Vesicles: Potential Implications for Plaque Biogenesis
Abnormal accumulation of Aβ (amyloid β) within AEL (autophagy–endosomal–lysosomal) vesicles is a prominent neuropathological feature of AD (Alzheimer's disease), but the mechanism of accumulation within vesicles is not clear. We express secretory forms of human Aβ 1–40 or Aβ 1–42 in Drosophila...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2014-02-01
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| Series: | ASN Neuro |
| Online Access: | https://doi.org/10.1042/AN20130044 |