De novo identification of toxicants that cause irreparable damage to parasitic nematode intestinal cells.

Efforts to identify new drugs for therapeutic and preventive treatments against parasitic nematodes have gained increasing interest with expanding pathogen omics databases and drug databases from which new anthelmintic compounds might be identified. Here, a novel approach focused on integrating a pa...

Full description

Bibliographic Details
Main Authors: Douglas P Jasmer, Bruce A Rosa, Rahul Tyagi, Christina A Bulman, Brenda Beerntsen, Joseph F Urban, Judy Sakanari, Makedonka Mitreva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007942