Subtype-specific differences in Gag-protease replication capacity of HIV-1 isolates from East and West Africa

Subtype-specific differences in Gag-protease replication capacity of HIV-1 isolates from East and West Africa

Abstract Background The HIV-1 epidemic in sub-Saharan Africa is heterogeneous with diverse unevenly distributed subtypes and regional differences in prevalence. Subtype-specific differences in disease progression rate and transmission efficiency have been reported, but the underlying biological mech...

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Bibliographic Details
Main Authors: Omotayo Farinre, Kamini Gounder, Tarylee Reddy, Marcel Tongo, Jonathan Hare, Beth Chaplin, Jill Gilmour, Phyllis Kanki, Jaclyn K. Mann, Thumbi Ndung’u
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Retrovirology
Subjects:
HIV-1 subtype
HIV-1 recombinants
Sub-Saharan Africa
HIV-1 replication capacity
HLA class I alleles
Online Access:https://doi.org/10.1186/s12977-021-00554-4

Internet

https://doi.org/10.1186/s12977-021-00554-4

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