Isolation, cloning and structural characterisation of boophilin, a multifunctional Kunitz-type proteinase inhibitor from the cattle tick.
Inhibitors of coagulation factors from blood-feeding animals display a wide variety of structural motifs and inhibition mechanisms. We have isolated a novel inhibitor from the cattle tick Boophilus microplus, one of the most widespread parasites of farm animals. The inhibitor, which we have termed b...
Main Authors: | Sandra Macedo-Ribeiro, Carla Almeida, Bárbara M Calisto, Thomas Friedrich, Reinhard Mentele, Jörg Stürzebecher, Pablo Fuentes-Prior, Pedro José Barbosa Pereira |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2230226?pdf=render |
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