Lovastatin protects against experimental plague in mice.

BACKGROUND: Plague is an ectoparasite-borne deadly infection caused by Yersinia pestis, a bacterium classified among the group A bioterrorism agents. Thousands of deaths are reported every year in some African countries. Tetracyclines and cotrimoxazole are used in the secondary prophylaxis of plague...

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Bibliographic Details
Main Authors: Saravanan Ayyadurai, Hubert Lepidi, Claude Nappez, Didier Raoult, Michel Drancourt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2880009?pdf=render