Interleukin-38 ameliorates poly(I:C) induced lung inflammation: therapeutic implications in respiratory viral infections

Abstract Interleukin-38 has recently been shown to have anti-inflammatory properties in lung inflammatory diseases. However, the effects of IL-38 in viral pneumonia remains unknown. In the present study, we demonstrate that circulating IL-38 concentrations together with IL-36α increased significantl...

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Bibliographic Details
Main Authors: Xun Gao, Paul Kay Sheung Chan, Grace Chung Yan Lui, David Shu Cheong Hui, Ida Miu-Ting Chu, Xiaoyu Sun, Miranda Sin-Man Tsang, Ben Chung Lap Chan, Christopher Wai-Kei Lam, Chun-Kwok Wong
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-020-03283-2