Development and Role in Therapy of Canakinumab in Adult-Onset Still’s Disease

Development and Role in Therapy of Canakinumab in Adult-Onset Still’s Disease

Adult-onset Still’s disease (AOSD) is a rare inflammatory disease of unknown etiology typically characterized by episodes of spiking fever, evanescent rash, arthralgia, leukocytosis, and hyperferritinemia. The pivotal role of interleukin (IL)-1 and other pro-inflammatory cytokines gives rise to the...

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Bibliographic Details
Main Authors: Paola Galozzi, Chiara Baggio, Sara Bindoli, Francesca Oliviero, Paolo Sfriso
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Pharmacology
Subjects:
Canakinumab
Adult-onset Still’s disease
Interleukin-1 beta
drug development
therapy
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01074/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01074/full

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