Dodecamer d-AGATCTAGATCT and a homologous hairpin form triplex in the presence of peptide REWER.

We have designed a dodecamer d-AGATCTAGATCT (RY12) with alternate oligopurines and oligopyrimidines tracts and its homologous 28 bp hairpin oligomer (RY28) that forms a triple helix only in the presence of a pentapeptide REWER. An intermolecular triplex is formed by the single strand invasion of the...

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Bibliographic Details
Main Authors: Amrita Das, Tapas Saha, Faizan Ahmad, Kunal B Roy, Vikas Rishi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3660596?pdf=render