Stress-induced NLRP3 inflammasome activation negatively regulates fear memory in mice

Stress-induced NLRP3 inflammasome activation negatively regulates fear memory in mice

Abstract Background Persistent inflammation dysregulation and cognitive decline have been associated with several trauma- and stress-related disorders such as posttraumatic stress disorder (PTSD) and anxiety disorder. Despite the abundant discoveries of neuroinflammation in such disorders, the under...

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Bibliographic Details
Main Authors: Yuan Dong, Shuoshuo Li, Yiming Lu, Xiaoheng Li, Yajin Liao, Zhixin Peng, Yunfeng Li, Lin Hou, Zengqiang Yuan, Jinbo Cheng
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Journal of Neuroinflammation
Subjects:
Fear memory
PTSD
NLRP3 inflammasome
Neuroinflammation
Postsynaptic density
Online Access:http://link.springer.com/article/10.1186/s12974-020-01842-0

Internet

http://link.springer.com/article/10.1186/s12974-020-01842-0

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