Skin and Systemic Inflammation in Schnitzler's Syndrome Are Associated With Neutrophil Extracellular Trap Formation

Skin and Systemic Inflammation in Schnitzler's Syndrome Are Associated With Neutrophil Extracellular Trap Formation

Schnitzler's syndrome is a rare autoinflammatory disorder characterized by interleukin-1ß-mediated and neutrophil-dominated inflammation. Neutrophil extracellular traps (NETs) are web-like structures of decondensed chromatin, histones, and antimicrobial peptides released by neutrophils. NETs we...

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Bibliographic Details
Main Authors: Hanna Bonnekoh, Jörg Scheffel, Jim Wu, Sheila Hoffmann, Marcus Maurer, Karoline Krause
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
Schnitzler's syndrome
neutrophil extracellular traps
neutrophils
autoinflammation
autoimmunity
neutrophilic dermatosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00546/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00546/full

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