Essential roles of mitochondrial and heme function in lung cancer bioenergetics and tumorigenesis
Abstract Contrary to Warburg’s hypothesis, mitochondrial oxidative phosphorylation (OXPHOS) contributes significantly to fueling cancer cells. Several recent studies have demonstrated that radiotherapy-resistant and chemotherapy-resistant cancer cells depend on OXPHOS for survival and progression. S...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2018-11-01
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| Series: | Cell & Bioscience |
| Online Access: | http://link.springer.com/article/10.1186/s13578-018-0257-8 |