Acute Promyelocytic Leukemia: Update on the Mechanisms of Leukemogenesis, Resistance and on Innovative Treatment Strategies

Acute Promyelocytic Leukemia: Update on the Mechanisms of Leukemogenesis, Resistance and on Innovative Treatment Strategies

This review highlights new findings that have deepened our understanding of the mechanisms of leukemogenesis, therapy and resistance in acute promyelocytic leukemia (APL). Promyelocytic leukemia-retinoic acid receptor α (PML-RARa) sets the cellular landscape of acute promyelocytic leukemia...

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Bibliographic Details
Main Authors: N. I. Noguera, G. Catalano, C. Banella, M. Divona, I. Faraoni, T. Ottone, W. Arcese, M. T. Voso
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cancers
Subjects:
apl
therapy
ngs
resistance
ato
atra
ascorbate
Online Access:https://www.mdpi.com/2072-6694/11/10/1591

Internet

https://www.mdpi.com/2072-6694/11/10/1591

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